HHVs AND LYMPHOPROLIFERATIVE DISORDERS
نویسندگان
چکیده
منابع مشابه
β-HHVs and HHV-8 in Lymphoproliferative Disorders
Similarly to Epstein-Barr virus (EBV), the human herpesvirus-8 (HHV-8) is a γ-herpesvirus, recently recognized to be associated with the occurrence of rare B cell lymphomas and atypical lymphoproliferations, especially in the human immunodeficiency virus (HIV) infected subjects. Moreover, the human herpesvirus-6 (HHV-6), a β-herpesvirus, has been shown to be implicated in some non-malignant lym...
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The immunomodulatory properties of the HLA-G molecule explain its relevance in malignancies. Our investigations in lymphoproliferative disorders show (i) a frequent and variable distribution of alternatively spliced HLA-G mRNA isoforms, (ii) a rare cell surface expression in diffuse large cell lymphomas with HLA class I loss in half of cases, and (iii) an increased serum level of sHLA-G in half...
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Lymphoproliferative disorders including non-Hodgkin lymphomas (NHL) are not uncommon neoplasms in patients infected with the human immunodeficiency virus (HIV). It has been established that HIV-infected individuals are more prone to develop certain lymphoproliferative disorders and lymphomas compared to non-infected individuals. The exact mechanisms underlying these associations is yet to be es...
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ژورنال
عنوان ژورنال: Mediterranean Journal of Hematology and Infectious Diseases
سال: 2011
ISSN: 2035-3006
DOI: 10.4084/mjhid.2011.043